Genome Annotation


Genome annotation is the description of an individual gene and its product, RNA or protein. It includes the function assigned to the gene product and brief evidence for the assigned function. Since there are many genes and products to analyze, the best process typically involves both manual and automated annotation. Structural annotation involves examining genetic elements such as open reading frames, gene structure and regulatory motifs. Functional annotation consists of assigning biological function (regulation, interactions, expression) to these elements. Several of today’s ongoing genome annotation projects include:

  • ENCyclopedia Of DNA Elements (ENCODE)
  • Entrez Gene
  • Ensembl
  • GENCODE
  • Gene Ontology Consortium
  • GeneRIF
  • RefSeq
  • Uniprot
  • Vertebrate and Genome Annotation Project (Vega)

Providers offering Genome Annotation (found 22)

Kovid BioAnalytics Pvt. Ltd.

India 13 years in service Genome Annotation: $15.00 USD (per hour)
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Kovid BioAnalytics is an Informatics and Analytics company based in India. We specialize in building software, web-based or standalone applications for various bioinformatics projects, data curation and analysis services, etc. With a team of Bioinformatics experts and Software Developers we provide the following services: 1) Bioinformatics Software Development 2) Website Design and Maintenance for Bioinformatics Services 3) Curation of Genomics/Proteomics Data 4) Manual annotation of bioinformatics data and data mining 5) Technical writing services 6) Significance Analysis of micro-array data

Years in service: 13

Bioinformatics services offered by Kovid BioAnalytics Pvt. Ltd.:

Service Description Price
ChIP-Seq Analysis $20.00 USD (per hour)
Differential Gene Expression Analysis We have experience in performing Differential Gene Expression Analysis for various researchers from institutes like Washington University at St. Louis, West Mead Hospital (Australia), Spain Cancer Center and Bar Ilan University (Israel), etc. $16.57 USD (per hour)
Genome Annotation $15.00 USD (per hour)
Metagenomic Analysis We provide Metagenomic Analysis services including data curation as well as analysis. $15.57 USD (per hour)
Other Services We have a team of 5 experienced Bioinformatics Experts and 2 web developers, that can built custom pipelines for NGS data analysis, web applications, data mining tools, websites, etc. $16.57 USD (per hour)
Variant Annotation We provide variant annotation services that include manual annotation of variants using public databases as well as annotation through automated pipelines/tools like GEMINI. $16.57 USD (per hour)

AC-Gen Reading Life S.L.

NGS provider Spain 13 years in service Genome Annotation: $400.00 USD (per sample)
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AC-Gen Reading Life is a Spanish pioneer company in the application of Next-Generation Sequencing technology (NGS) for clinical use. We have the NGS Ion Torrent™ platform available in our lab, and can carry out data analysis. Ion Torrent™ technology for NGS is the fastest and cost effective technology in the market for DNA analysis.

Mission: to improve the health and quality of life of people affected by genetic diseases.

Objectives: To provide high quality genetic analysis and cost-effective to help the implementation of personalized genomic medicine, as well as foster the development of partnerships in the field of research.

Years in service: 13

Bioinformatics services offered by AC-Gen Reading Life S.L.:

Service Description Price
Base Calling Torrent server and Ion reporter $300.00 USD (per sample)
Genome Annotation Bacteria genome $400.00 USD (per sample)
Targeted Capture Analysis Base calling, annottation $300.00 USD (per sample)

Igenbio, Inc.

United States of America 13 years in service Genome Annotation: Inquire
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Expertise:

Igenbio, Inc. develops genome analysis products and services for the life science industry. Our scientists have broad experience in both in silico and wet lab sequencing, research and development with more than 100 relevant publications in these areas. Igenbio has a proven track record of delivering scientific results for academic, governmental, and industrial institutions for two decades.

Our expertise includes, but is not limited to:

  • Whole Genome Sequencing
  • RNA-Sequencing
  • Metatranscriptomics Sequencing
  • Metagenome Sequencing
  • Common and custom amplicon sequencing
  • Genome Assembly & Annotation
  • RNA-Seq Analysis
  • Amplicon Sequencing Analysis
  • Metagenome Analysis
  • Genome ORF calling: Eukaryotes and Prokaryote Genomes
  • Pathway Analysis
  • Metabolic Reconstruction
  • SNP Discovery & Analysis
  • Comparative Genomics
  • Available for all organisms, including humans, animals, plants, bacteria, and viruses.
  • Haploid, diploid or polyploid assemblies

Infrastructure:

Igenbio has a large, secure cloud infrastructure that can expand to meet any project demands you may have - from large number of samples to quick turnaround times. Please inquire for more information.

At Igenbio, Inc. security of your data is a top priority. Your data is protected by best practices in physical and data security measures. This includes 24/7 physical security and monitoring, and the best available encryption for storage and transmission. Our employees are trained and knowledgeable in data security best practices.

Years in service: 13

Bioinformatics services offered by Igenbio, Inc.:

Service Description Price
Base Calling Inquire
Comparative Genome Analysis Inquire
Differential Gene Expression Analysis Inquire
Genome Annotation Gene Annotation and Functional Assignments placing genes into their functional or metabolic context utilizing KEGG Pathways, Gene Ontology, and the ERGO database. Optional - Identification of Antibiotic Resistance - including the genes, pathways, and specific drugs Inquire
Metagenomic Analysis - Quality analytics of sequence reads - State of the art sample processing using academically-proven tools such as DADA2 and Kraken2 that work on all sequencing platforms such as Illumina & Pacific Biosciences. - Fast and accurate taxa identification using state-of-the-art machine learning algorithms that can identify taxa down to the species level. - Supports public databases (such as Silva,… Inquire
Microbiome Analysis - Quality analytics of sequence reads - State of the art sample processing using academically-proven tools such as DADA2 or Kraken2 that work on all sequencing platforms such as Illumina & Pacific Biosciences. - Fast and accurate taxa identification using state-of-the-art machine learning algorithms that can identify taxa down to the species level. - Supports public databases (such as Silva, Gree… Inquire
SNP / Indel Calling Inquire
SNP/SV/CNV Discovery Inquire
Transcriptome Annotation Inquire
Transcriptome Annotation Inquire
Transcriptome de novo Assembly Inquire
Variant Annotation Inquire
Whole Genome de novo Assembly All current sequencing technologies support - Illumina, PacBio, Oxford Nanopore, 10x, Hi-C, Ion Torrent, and others. Igenbio scientists utilize a multitude of assembly strategies - denovo, reference based, hybrid, metagenomic, and others. Inquire

Diagnomics

United States of America Genome Annotation: Inquire
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Bioinformatics services offered by Diagnomics:

Service Description Price
Base Calling Inquire
Genome Annotation Inquire
SNP / Indel Calling Inquire
SNP / Indel Mapping Inquire
Targeted Capture Analysis Inquire
Variant Annotation Inquire

intelliseq

Poland Genome Annotation: Inquire
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Bioinformatics services offered by intelliseq:

Service Description Price
ChIP-Seq Analysis Inquire
Custom scripting and special projects Inquire
Differential Gene Expression Analysis Inquire
Genome Annotation Inquire
Metagenomic Analysis Inquire
Methylation Analysis Inquire
Other Services Inquire
Read Filtering and Cleaning Inquire
Small RNA Mapping Inquire
SNP / Indel Calling Inquire
SNP / Indel Mapping Inquire
Transcriptome Annotation Inquire
Transcriptome Mapping Inquire
Variant Annotation Inquire

Bionivid Technology Private Limited

NGS provider India 15 years in service Genome Annotation: Inquire
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Whole Genome Sequencing, Transcriptome Sequencing (RNASEQ /miRNA), Metagenomics, Epigenomics, etc. to our credit; with 100+ co-authorship articles, highest in Indian industry. Recent past, we have also optimized multi-omics Single Cell Genomics solutions to cater to various research needs.

Years in service: 15

Bioinformatics services offered by Bionivid Technology Private Limited:

Service Description Price
Base Calling Inquire
ChIP-Seq Analysis Inquire
Comparative Genome Analysis Inquire
Custom scripting and special projects Inquire
Differential Gene Expression Analysis Inquire
Genome Annotation Inquire
Genome Mapping Inquire
Methylation Analysis Inquire
Read Filtering and Cleaning Inquire
Small RNA Annotation Inquire
Small RNA Mapping Inquire
SNP / Indel Calling Inquire
SNP / Indel Mapping Inquire
SNP/SV/CNV Discovery Inquire
Targeted Capture Analysis Inquire
Transcriptome Annotation Inquire
Transcriptome de novo Assembly Inquire
Transcriptome Mapping Inquire
Variant Annotation Inquire
Whole Genome de novo Assembly Inquire

Biosof LLC

United States of America Genome Annotation: Inquire
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Bioinformatics services offered by Biosof LLC:

Service Description Price
Comparative Genome Analysis Inquire
Custom scripting and special projects Inquire
Differential Gene Expression Analysis Inquire
Genome Annotation Inquire
Genome Mapping Inquire
Read Filtering and Cleaning Inquire
SNP / Indel Calling Inquire
SNP / Indel Mapping Inquire
SNP/SV/CNV Discovery Inquire
Transcriptome Annotation Inquire
Transcriptome de novo Assembly Inquire
Variant Annotation Inquire
Whole Genome de novo Assembly Inquire

Next Generation Intelligence

NGS provider Italy Genome Annotation: Inquire
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Bioinformatics services offered by Next Generation Intelligence:

Service Description Price
Base Calling Inquire
ChIP-Seq Analysis Inquire
Custom scripting and special projects Inquire
Differential Gene Expression Analysis Inquire
Exome Analysis Inquire
Genome Annotation Inquire
Genome Mapping Inquire
Methylation Analysis Inquire
Other Services Inquire
Read Filtering and Cleaning Inquire
Small RNA Annotation Inquire
Small RNA Mapping Inquire
SNP / Indel Calling Inquire
SNP / Indel Mapping Inquire
SNP/SV/CNV Discovery Inquire
Targeted Capture Analysis Inquire
Transcriptome Annotation Inquire
Transcriptome de novo Assembly Inquire
Transcriptome Mapping Inquire
Variant Annotation Inquire

Cytognomix Inc.

Canada Genome Annotation: Inquire
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Bioinformatics services offered by Cytognomix Inc.:

Service Description Price
Genome Annotation Inquire
Variant Annotation Inquire

Station X

United States of America 15 years in service Genome Annotation: $85.00 USD (per sample)
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We offer a powerful genomics software platform that makes various bioinformatics tasks fairly straightforward to perform and deliver to customers. We also wrap this product with various service offerings for folks interested in one-off projects that deliver results rather than just subscribing to a software solution and then do the work themselves. We are comfortable with both scenarios. We are well versed in working with RNA-Seq, Genomes, Exomes, targeted panels, miRNA-Seq, Copy Number, Gene Expression, Protein Expression, and DNA Methylation from the level of raw sequencing reads or chip data all the way through to statistically-driven and knowledge-driven interpretations.

Expertise:

We are experienced in developing bioinformatics pipelines, providing data management solutions, analyzing the data using statistical methods and knowledge driven methods, and delivering professional-grade results. We are most familiar with human genomics projects, but have experience with other organisms as well. We are most focused on supporting sequencing projects, but are very capable of supporting array and PCR-based projects as well.

Infrastructure:

We leverage Amazon Web Services for most of our storage (EBS & S3) and computational resources (EC2). We are not frivolous about security, and we can provide you with security documentation to demonstrate how we leverage cloud resources while keeping best-in-class security. We also have powerful 16-core machines in our own private cloud that we leverage for service projects as well.

Years in service: 15

Bioinformatics services offered by Station X:

Service Description Price
Comparative Genome Analysis $2500.00 USD (flat price)
Custom scripting and special projects $275.00 USD (per hour)
Differential Gene Expression Analysis $1655.00 USD (flat price)
Exome Analysis $2500.00 USD (flat price)
Genome Annotation $85.00 USD (per sample)
Other Services Visualizations, Report Generation, Customizations to our platform, Training, Scientific support, Presentation support, etc. $300.00 USD (per hour)
Read Filtering and Cleaning $115.00 USD (per sample)
Small RNA Annotation $85.00 USD (per sample)
Small RNA Mapping $100.00 USD (per sample)
SNP / Indel Calling $100.00 USD (per sample)
SNP / Indel Mapping $100.00 USD (per sample)
SNP/SV/CNV Discovery $100.00 USD (per sample)
Transcriptome Annotation $85.00 USD (per sample)
Transcriptome Mapping $100.00 USD (per sample)
Variant Annotation $85.00 USD (per sample)

Computomics

Germany 14 years in service Genome Annotation: Inquire
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Bioinformatics Services for Plant Scientists and Breeders by Computomics

At Computomics.com, we deliver in-depth NGS analyses. We start by identifying your breeding or research goals, devise a sequencing strategy to achieve them and define the project deliverables and timeline through an initial consultation. Our methods include the latest algorithms from the bioinformatics community.

We protect the security of your data. We use high-performance servers in a high-security data center with two-factor access control mechanisms. During the analysis, we use transparent, reliable processes and quickly deliver highly reproducible results in constant feedback with you, via virtual or onsite meetings at your location.

Our NGS products are exclusively focusing on plant species and their interacting microbes, and include: 

  • Reference genome assembly: experience with polyploids and genomes up to 22 Gbp
  • Genome annotation: ab initio gene and transcript isoform prediction, protein function, ncRNA annotation
  • Genomic variance analysis and comparison: for marker development, phylogenetic studies, and comparative genomics
  • Bulk segregation analysis, genotyping, marker development
  • Differential gene expression, de novo transcriptome assembly
  • World’s fastest, most accurate metagenomics
  • Statistically sound epigenetics
  • Genomic selection with continuous model improvement

Computomics collaborates with world-leading scientists, opening up an unprecedented opportunity for breeders and plant scientists. We provide data of the highest possible quality that expedite your crop improvement programs.

Years in service: 14

Bioinformatics services offered by Computomics:

Service Description Price
Comparative Genome Analysis We excel at managing complex crop genomic variance studies. Our analysis can help you obtain a set of genomic markers to enhance rational and controlled breeding procedures. Markers may include single nucleotide polymorphisms (SNPs), insertions and deletions (InDels), copy number variations (CNVs) or structural variants (SVs). Taking into account the properties of your plant of interest and the … Inquire
Differential Gene Expression Analysis Gene expression studies, or RNAseq allow you to sequence the entire transcriptome of a plant, and provide valuable applications in crop improvement programs We and our collaborators have published peer reviewed methods for accurate gene expression analysis. Our RNAseq analyses can determine exact gene expression levels including splice variants. Using machine learning techniques, we identify dif… Inquire
Genome Annotation We perform de novo genome annotation using the latest in silico predictive approaches and RNAseq reads. We offer two machine learning-based gene prediction methods that can be trained to recognise biological features in your crop’s genome. The resources we use to build an annotation map include existing annotations for related organisms, RNAseq data, and PacBio complete isoforms. We use all avai… Inquire
Metagenomic Analysis World’s Fastest, Most Accurate Metagenomics Plants interacts constantly with soil-borne microbes. These interactions vary from symbiotic to pathogenic. In a metagenomics study of the rhizosphere, DNA or RNA are sequenced using next generation sequencing instruments. Sequences that do not originate from the plant host are analysed to identify genes and species contained within the sample. A tax… Inquire
Methylation Analysis Statistically Sound Epigenetics Non-genetic factors affect crops traits and phenotypes. Identifying epigenetic patterns allow breeders and plant scientists to uncover expression correlations and non-genetically inherited gene regulation patterns. We specialize in crop epigenetics. Methylation of cytosine residues is a known mechanism for gene silencing and gene expression regulation. We use bi… Inquire
Other Services Bioinformatics Consulting In addition to our next-generation sequencing (NGS) products and services, We also offer individual consulting services. With a team of scientists and partners who are thought leaders in crop genomics, we give impartial advice, independent of any sequencing platform, technology or tool suite. Each consultation is unique, please contact us to receive a quote for your sp… Inquire
Other Services Introgression and Insertion Delineation Next-generation sequencing is a great tool for molecular characterisation of seeds with genetic modifications or introgressions. We can provide answers to many regulatory and safety related questions, such as: At how many sites was the DNA integrated into the plant genome? What is the exact sequence of each insert? Is the sequence rearranged with respect t… Inquire
Other Services Genomic Selection with Continuous Model Improvement Genomic Selection with Continuous Model Improvement Genomic selection is a highly successful strategy to predict breeding values in plants. Advances in sequencing and high-throughput variant discovery enable the collection of tens of thousands of markers for hundreds of plants, providing exciting opportunities for unleashing the full power of g… Inquire
Read Filtering and Cleaning Inquire
Whole Genome de novo Assembly We have a deep understanding of both de novo and reference-based genome assembly of large crop genomes. It is crucial to first develop an effective strategy before selecting the appropriate sequencing technology and bioinformatics tools. A de novo genome assembly project must address sources of error up front, like sequence bias and read quality. A crucial point is quality control. We compare o… Inquire

Labindia-GPOD

India 16 years in service Genome Annotation: $500.00 USD (per sample)
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We provide NGS data analysis services using public domain tools as well as CLC bio workbenches. Our services include primary, secondary and tertiary data analysis of NGs data from all platforms. Data analysis steps include read QC check, Assembly and metrics, Annotation, Variant detection, and annotation and biological interpretations. We also enter in to joint projects as industry partners.

Years in service: 16

Bioinformatics services offered by Labindia-GPOD:

Service Description Price
Exome Analysis Exome analysis at our facility is performed using CLC bio Cancer workbench which helps in find and annotate variants more accurately. $200.00 USD (per sample)
Genome Annotation We perform Genome annotation using BLAST and BLAST2Go tools. We have FPGA based local facility which speeds up the BLAST process $500.00 USD (per sample)
Genome Mapping We perform reference genome mapping using CLC bio Genomic recent version and also available public domain tools to benchmark the results. CLc bio has currently released faster genome mapper. We perform post assembly metrics to check correctness of reference assembly. $150.00 USD (per sample)
Transcriptome de novo Assembly Transcriptome de novo assembly and read map back is performed using CLC bio genomic workbench and other public domain tools. This analysis is followed by transcriptome annotation and tertiary analysis like pathaway findings. $500.00 USD (per sample)
Variant Annotation Variant annotation is performed using CLC bio Cancer Research Workbench. $600.00 USD (per sample)
Whole Genome de novo Assembly WGS de novo assembly is performed using latest version of the CLC bio Genomic Workbench and available public domain tools. End analysis helps to benchmark the results and robustness of the assembly. Post assembly metrics are performed to check the quality of the assembly $500.00 USD (per sample)

NXT-Dx

NGS provider Belgium 15 years in service Genome Annotation: $170.00 USD (per hour)
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At NXT-Dx we can offer SE50, PE50 and PE100 sequencing on the Illumina HiSeq. On top of this we can also offer different sequencing settings on the Illumina MiSeq and shortly we will also be able to offer sequencing on the Illumina NextSeq.

We can offer sequencing of already prepared libraries but we can also offer full-scope projects whereby we receive cells, tissue, gDNA or RNA and take care of the sample preparation, library prep, sequencing and bio-informatics analysis.

We have worked with samples from all kind of species (mammalian, plant, bacterial) and all kind of cell types.

We pride ourselves in having close contact with our customers and only one single contact point. Also after the delivery of the data, we remain available to answer any questions customers might have on their data, their analysis, etc.

Years in service: 15

Bioinformatics services offered by NXT-Dx:

Service Description Price
Base Calling $170.00 USD (per hour)
ChIP-Seq Analysis $170.00 USD (per hour)
Comparative Genome Analysis $170.00 USD (per hour)
Custom scripting and special projects $170.00 USD (per hour)
Differential Gene Expression Analysis $170.00 USD (per hour)
Exome Analysis $170.00 USD (per hour)
Genome Annotation $170.00 USD (per hour)
Genome Mapping $170.00 USD (per hour)
Methylation Analysis $170.00 USD (per hour)
Read Filtering and Cleaning $170.00 USD (per hour)
Small RNA Annotation $170.00 USD (per hour)
Small RNA Mapping $170.00 USD (per hour)
Targeted Capture Analysis $170.00 USD (per hour)
Transcriptome Annotation $170.00 USD (per hour)
Transcriptome Mapping $170.00 USD (per hour)
Variant Annotation $170.00 USD (per hour)

Omega Bioservices

NGS provider United States of America 14 years in service Genome Annotation: $221.00 USD (per sample)
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Our facility is unique because we offer the full range of NGS service from sample extraction through to data analysis. Sample extraction capabilities and expertise cover the entire spectrum of both environmental and clinical sample types.

Years in service: 14

Bioinformatics services offered by Omega Bioservices:

Service Description Price
Base Calling Demultiplex data and convert BCL files to FASTQ files $110.00 USD (per sample)
ChIP-Seq Analysis ChIP-Seq is a technique to identify DNA loci bound by a specific protein. The standard output of ChIP-seq analysis includes peak call and motif enrichment at binidng sites. $332.00 USD (per sample)
Custom scripting and special projects We provide study specific bioinformatics analysis (known as tertiary analysis). such as (not limited to) 1) process secondary sequencing data analysis for a variety of platforms such as Nanostring, Nanopore, single cell expression. 2) integrative analysis across sequencing platforms (such as DNA-seq, RNA-seq, Chip-seq) 3) integrate meta/clinical information, perform association study and build p… $60.00 USD (per hour)
Differential Gene Expression Analysis Custom bioinformatics for non-model organisms, or other unusual cases. Does not include setup fee. $110.00 USD (per sample)
Differential Gene Expression Analysis Identify differentially expressed genes among samples using RNA-seq technique. Human, mouse, rat, fruit fly, cattle, pig, chicken, zebrafish, C. elegans, maize, thale cress, Japonica rice (Oryza sativa) and yeast, up to 7.5gb/sample. $56.00 USD (per sample)
Exome Analysis Whole exome sequencing involves capturing the coding region of the genome, or exons (EXpressed regiONS). SNVs and indels are the most important and abundant types of variation in exons. Human exome analysis provided free of charge with sequencing service. $332.00 USD (per sample)
Genome Annotation Annotation is the process by which pertinent information about these raw DNA sequences is added to the genome databases. This involves describing different regions of the sequence and identifying which regions can be called genes. $221.00 USD (per sample)
Genome Mapping Genome mapping is a technique used to assign the location of a particular gene on a chromosome and measure their relative locations and distances between genes. Mapping to many model organisms provided free of charge with sequencing service. $110.00 USD (per sample)
Metagenomic Analysis Metagenomic analysis involves the identification and quantification of genetic material from environmental, uncultured microorganisms. Analysis involving only 16S rRNA amplicon sequences are provided free of charge with sequencing service. $551.00 USD (per sample)
Methylation Analysis The processing of bisulfite sequencing data includes sequence alignment and the quantification of absolute DNA methylation at base resolution. Methylation analysis for data generated from the Illumina TruSeq kit are provided free of charge with sequencing service. $553.00 USD (per sample)
Read Filtering and Cleaning Examination of sequencing quality and removal of low quality reads prior to downstream analysis provided free of charge with sequencing service if desired. $110.00 USD (per sample)
Small RNA Annotation Small RNA (miRNA, lincRNA, snoRNA, snRNA, tRNA) libraries will be mapped to the reference genome and annotated using public databases e.g. miRBase. $332.00 USD (per sample)
Small RNA Mapping Small RNA (miRNA, lincRNA, snoRNA, snRNA, tRNA) libraries will be mapped to the reference genome and annotated using public databases e.g. miRBase. $221.00 USD (per sample)
SNP / Indel Calling Identify SNPs and Indels in the region of interested, using DNA sequencing. Analysis for human, mouse, and rat provided free of charge with sequencing service. $332.00 USD (per sample)
SNP / Indel Mapping Mapped to the reference genome and annotated using public database. Analysis for human, mouse, and rat provided free of charge with sequencing service. $332.00 USD (per sample)
SNP/SV/CNV Discovery Variants discovery. Analysis for human, mouse, and rat provided free of charge with sequencing service. $332.00 USD (per sample)
Targeted Capture Analysis Variant call, gene annotation. Provided free of charge with sequencing service. $332.00 USD (per sample)
Transcriptome Annotation Annotate or predict functions of transcribed genes using well know gene ontology tools. $332.00 USD (per sample)
Transcriptome de novo Assembly Identify and quantify putative mRNA transcripts using RNA-seq data for unannotated species. $553.00 USD (per sample)
Transcriptome Mapping Map mRNAs to either the reference or the assembled genome. $332.00 USD (per sample)
Variant Annotation Identified variants will be mapped to the reference genome and annotated using public database. Analysis for human sequences provided free of charge with sequencing service. $332.00 USD (per sample)
Whole Genome de novo Assembly Prices vary according to genome type. Please contact our Science Project Team. Some small genome assembly provided free of charge with sequencing service. $3315.00 USD (per sample)

iBinom

United States of America 13 years in service Genome Annotation: $50.00 USD (per sample)
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iBinom is a cloud-based NGS data analysis service designed for clinical inherited disease diagnostics needs. We deliver ultrafast, accurate and easy-to-use genome analysis service for medical professionals around the world. Built-in raw data pre-processing ensures a high confidence output. Proprietary machine learning algorithms and sophisticated filtration system leads to ultimately precise interpretation results and reports a short-list of actionable variants. We support all popular data formats: fastq, fastq.gz, bam, vcf, vcf.gz We are platform-independent: Roche Junior, Roche 454, Illumina, Life Technologies

Years in service: 13

Bioinformatics services offered by iBinom :

Service Description Price
Exome Analysis We offer exome analysis from raw data processing to variant reporting. Our pipeline implements thorough quality control and finely tuned algorithms tuned to achieve the highest precision, sensitivity and specificity of analysis. Our QC system forewarns of potentially missed reporting variants in uncovered regions. We guarantee reproducible and ultimately accurate results. $400.00 USD (per sample)
Genome Annotation We provide an intuitive and flexible genome data filtration system that shortens the path to detecting the causative variants for inherited disease diagnostics. All relevant databases, scores and essential knowledge are plugged into the system. We automatically updates key data points on a regular basis. Free data re-analysis is available. We offer target panel, exome and whole genome variant a… $50.00 USD (per sample)

World Fusion US

United States of America 20 years in service Genome Annotation: Inquire
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World Fusion is a well-established bioinformatics and cheminformatics software developer and services supplier with offices in Japan and the US. We have been at the forefront of developing genomic and drug discovery research tools since our early work on the Human Genome Project, and offer unparalleled reliability and expertise in our services.

Our customizable services include NGS data analysis, in-silico research services, and we are annotation specialists offering the most comprehensive correlations between genes, proteins, diseases, and chemicals.

The majority of the information is generated from our proprietary genomic and drug discovery research platform and knowledge base that we have been upgrading and building upon for over 10 years. It is comprised of original in-house data, curated information from over 60 top public data sets, and a chemical dictionary containing over 75 million non-redundant chemical compounds.

Our more recently added metagenomic and metaranscriptomic analysis services are carried out using state-of-the-art, original in-house software applications.

We offer MANY additional services, please contact us about your specific needs.

Years in service: 20

Bioinformatics services offered by World Fusion US:

Service Description Price
Genome Annotation Gene/Protein Annotation Services: • Identify relationships beween genes and proteins or diseases • Cite connections between genes or proteins and chemicals • Extract bind/inhibit chemicals from proteins or genes • Examine SNP information and association with disease • Find bind/inhibit compounds and therapeutic targets from associated disease • Gene expression prioritization from RNAseq dat… Inquire
Metagenomic Analysis Analysis of the transcripts present in the RNA-seq data through frequency analysis of functional categories from the selected protein DB (such as COG). Result files include annotations from ligand information with related chemical compounds, pathways, and iPath. •Biological function information •Metabolic compound info from proteins •Multiple sample analysis •Bar charts, pie charts, and fr… Inquire
Metagenomic Analysis 16S/28S/ITS rRNA metagenomic data analysis of the composition and diversity of microbial or fungal species from natural environments. Interactive HTML report with taxonomically classified charts & graphs, read counts, 2D, 3D, and interactive PCA plots, heat clustering maps, and self-organizing maps. •Metagenomic analysis of bacteria from species classification of taxonomic rank •Fungal metag… Inquire
Other Services In-silico target exploration from disease - therapeutic targets, related drugs, gene and protein targets, etc. Includes an extensive annotation table with information about the disease and related diseases, SNPs, compounds, drugs, genes, proteins, and tissues. Inquire
Other Services Target prediction from chemical structure - prediction of target proteins which is based on: 1.5M compounds, 5500 protein, and 5M interactions. Inquire
Other Services Target Prioritization helps with the selection of gene/proteins for your research, from gene expression/SNV data - the analysis provides information about compounds and the activities, assays, SNPs, diseases, domains, pathways, and references. Inquire
Transcriptome Annotation Expression data analysis includes over 20 kinds of annotation such as: genes (ontology, pathways), proteins, diseases, domains, ligands, and compounds. Prioritization of genes and proteins can be executed from a variety of directions. •Statistical processing from expression values •Conversion and active compound information from proteins •Inhibitor compounds and inhibitory active compounds … Inquire
Variant Annotation Analysis focuses on the SNP variant amino acid change and includes annotations of related diseases, genes, proteins, assays, ligands, SNPs, domains, and chemical compounds (active compound information, crystal structure, chemical formula, activities, etc.). •Non-synonomous SNPs and chemicals influenced by mutation location •Information about the compounds and proteins affected by the amino a… Inquire

Arizona Genomics Institute

NGS provider United States of America 21 years in service Genome Annotation: Inquire
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The Arizona Genomics Institute (AGI) offers DNA extraction, sequencing, and bioinformatic analyses. AGI has a two-decade long experience with isolation and purification of high-molecular weight DNA from plants and many other organisms. Since 2015, AGI is a PacBio Certified Service Provider, and currently operates the Sequel IIe instrument. Since the beginning of the genomics era, AGI has been a leader in genome analyses (BAC libraries, WGS sequencing, physical mapping) to the plant research realm, being the major lead in the rice and maize genome sequencing projects. So far, AGI's Service Center has developed more than 800 projects. Most of them are whole-genome shotgun sequencing projects, but a relevant part consists in Iso-Seq and amplicon sequencing projects. AGI has extensive experience in extracting high-molecular weight, highly-pure DNA for any sequencing application, from difficult plant, fungal, and metagenomic samples.

Years in service: 21

Bioinformatics services offered by Arizona Genomics Institute:

Service Description Price
Genome Annotation inquire for details Inquire
Whole Genome de novo Assembly inquire for details Inquire

ContigExpress, LLC

United States of America 16 years in service Genome Annotation: Inquire
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ContigExpress is the leading integrated genomics data service provider. We offer genomic project management, data analysis, and bio-IT consulting services. Our unique value to our clients lies in our deep understanding of both biology and informatics. From project consultation, bio-IT infrastructure implementation, to data analysis, our experienced scientists deliver not only cost-effective customized informatic solutions but also their expert insights.

Our team consists of Ph.D.-level computational biologists with extensive training and professional practice in bioinformatics and genomic research. We understand both your cutting-edge research and your informatics challenges. We enable you and your team to extract actionable information from the vast amount of genomic data in a cost-effective and timely fashion.

We at ContigExpress strive to deliver affordable expert genomic data solutions to researchers and clinicians. We place the utmost emphasis on information confidentiality, data security, and data integrity. Please schedule a complimentary project discussion with one of our expert bioinformaticians to discover how we can help you move your genomics research forward!

Years in service: 16

Bioinformatics services offered by ContigExpress, LLC:

Service Description Price
ChIP-Seq Analysis Following is a list of common analysis items for ChIP-Seq. One of our expert bioinformaticians will work closely with you to identify a custom analysis workflow most appropriate for your project. 1) Experiment design consultation 2) Data QC and clean up 3) Alignment to a reference with mapping statistics 4) Peaking calling with or without control samples 5) Gene assignment and peak annotation 6)… Inquire
Differential Gene Expression Analysis Following is a list of common analysis items for RNA-Seq. One of our expert bioinformaticians will work closely with you to identify a custom analysis workflow most appropriate for your project. 1) Experiment design consultation 2) Data QC and clean up 3) Alignment to a reference with mapping statistics 4) Gene and transcript-based quantitation, RPKM/FPKM-based quantitation, Raw hit count-based … Inquire
Exome Analysis Following is a list of common analysis items for Targeted Resequencing and Exome Sequencing. One of our expert bioinformaticians will work closely with you to identify a custom analysis workflow most appropriate for your project. 1) Experiment design consultation 2) Data QC and clean up 3) Alignment to a reference with mapping statistics 4) Local realignment 5) SNP and small indel calling 6) SNP… Inquire
Genome Annotation Following is a list of common analysis items for Genome Annotation. One of our expert bioinformaticians will work closely with you to identify a custom analysis workflow most appropriate for your project. 1) Experiment design consultation 2) Gene prediction with or without RNASeq data 3) BLAST-based gene function annotation 4) Written project report with analysis methods, publication-ready graph… Inquire
Genome Mapping Following is a list of common analysis items for Whole Genome Resequencing. One of our expert bioinformaticians will work closely with you to identify a custom analysis workflow most appropriate for your project. 1) Experiment design consultation 2) Data QC and clean up 3) Alignment to a reference with mapping statistics 4) Local realignment 5) SNP and small indel calling 6) SNP/small indel char… Inquire
Metagenomic Analysis Following is a list of common analysis items for Metagenomics Sequencing. One of our expert bioinformaticians will work closely with you to identify a custom analysis workflow most appropriate for your project. 1) Experiment design consultation 2) Data QC and clean up 3) Sequence assembly 4) Biodiversity analysis and binning 5) Gene predication and functional annotation 6) Gene Ontology and path… Inquire
Methylation Analysis Following is a list of common analysis items for Methylation Sequencing, including MeDIP-Seq, hMeDIP-Seq, RRBS / Targeted Bisulfite-Seq, WGBS, and 5-mc RNA-Seq. One of our expert bioinformaticians will work closely with you to identify a custom analysis workflow most appropriate for your project. 1) Experiment design consultation 2) Data QC and clean up 3) Methylation state-sensitive mapping 4) … Inquire
Other Services We are a professional bioinformatics service provider and we are happy to provide customized informatic solutions to your unique research and business needs. Please feel free to reach out to us to discuss how we can help you. Inquire
Small RNA Annotation Following is a list of common analysis items for small RNA-Seq. One of our expert bioinformaticians will work closely with you to identify a custom analysis workflow most appropriate for your project. 1) Experiment design consultation 2) Data QC, adaptor removal, and size selection 3) Read characterization by mapping to a reference genome sequence, known RNA families (e.g., Rfam), and known micr… Inquire
Small RNA Mapping Following is a list of common analysis items for small RNA-Seq. One of our expert bioinformaticians will work closely with you to identify a custom analysis workflow most appropriate for your project. 1) Experiment design consultation 2) Data QC, adaptor removal, and size selection 3) Read characterization by mapping to a reference genome sequence, known RNA families (e.g., Rfam), and known micr… Inquire
SNP/SV/CNV Discovery Following is a list of common analysis items for Whole Genome Resequencing. One of our expert bioinformaticians will work closely with you to identify a custom analysis workflow most appropriate for your project. 1) Experiment design consultation 2) Data QC and clean up 3) Alignment to a reference with mapping statistics 4) Local realignment 5) SNP and small indel calling 6) SNP/small indel char… Inquire
Targeted Capture Analysis Following is a list of common analysis items for Targeted Resequencing and Exome Sequencing. One of our expert bioinformaticians will work closely with you to identify a custom analysis workflow most appropriate for your project. 1) Experiment design consultation 2) Data QC and clean up 3) Alignment to a reference with mapping statistics 4) Local realignment 5) SNP and small indel calling 6) SNP… Inquire
Transcriptome Annotation Following is a list of common analysis items for De Novo Sequencing. One of our expert bioinformaticians will work closely with you to identify a custom analysis workflow most appropriate for your project. 1) Project consultation 2) Transcriptome annotation (molecular functions, Gene Ontology and pathway) 3) Written project report with analysis methods, publication-ready graphics, and references Inquire
Transcriptome de novo Assembly Following is a list of common analysis items for De Novo Sequencing. One of our expert bioinformaticians will work closely with you to identify a custom analysis workflow most appropriate for your project. 1) Experiment design consultation 2) Data QC and clean up 3) Transcriptome assembly, scaffolding and gap closure 4) Gene annotation (molecular function, Gene Ontology and pathways) 5) SNP disc… Inquire
Whole Genome de novo Assembly Following is a list of common analysis items for De Novo Sequencing. One of our expert bioinformaticians will work closely with you to identify a custom analysis workflow most appropriate for your project. 1) Experiment design consultation 2) Data QC and clean up 3) Contig assembly 4) Scaffolding and gap closure 5) Gene/ORF prediction 6) Gene annotation and classification via database search and… Inquire

genexa Ltd

Switzerland 11 years in service Genome Annotation: Inquire
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genexa is a genomic data analysis provider located in Switzerland. Our bioinformatics services are centered around de novo assembly of genomes and metagenomes. We focus on processing, analysis, and interpretation of your genomics data. For all our fields of expertise, we offer to perform the entire analysis workflow from raw data to documentation, but also consulting and troubleshooting if required. genexa also provides resources to run computationally demanding tasks for specific jobs if you have an existing analysis workflow, but lack the computational resources to run it on large amounts of data. For further information check: genexa.ch

Years in service: 11

Bioinformatics services offered by genexa Ltd:

Service Description Price
Base Calling Inquire
Comparative Genome Analysis Inquire
Custom scripting and special projects Inquire
Differential Gene Expression Analysis Inquire
Genome Annotation Inquire
Metagenomic Analysis Inquire
Microbiome Analysis Inquire
Other Services We offer bioinformatics services using long-read sequencing (PacBio & Oxford Nanopore Technologies). We have several years of experience using third-gen. technologies, mainly applying these technologies for de novo assembly of individual genomes and metagenomes. We also offer transcriptomic analyses using long-read technologies. If you want to start using PacBio or Oxford Nanopore Technologies,… Inquire
Read Filtering and Cleaning Inquire
SNP / Indel Calling Inquire
Transcriptome Annotation Inquire
Variant Annotation Inquire
Whole Genome de novo Assembly Inquire

Breakthrough Genomics

NGS provider 8 years in service Genome Annotation: $300.00 USD (per sample)
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Bioinformatics services offered by Breakthrough Genomics:

Service Description Price
Genome Annotation Genome data analysis and clinical reporting $300.00 USD (per sample)
Genome Annotation If the client uses our software platform for annotation, it is free. Inquire

Inocras Inc.

NGS provider 3 years in service Genome Annotation: $335.00 USD (per hour)
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  • End-to-end diagnostics services featuring whole genome sequencing - for clinical applications of cancer, rare disease and MRD. Below are the listed applications for research:

Biopharmaceuticals and biotechnology --- Identify candidate biomarkers that correlate with outcomes Understand responders vs. non-responders during or post clinical trials Accelerate clinical trial enrollment by identifying patients for rare indications Analyze clinical trial results for efficiency and safety profile Leverage genetic information for label expansion with real world data Provide genetic testing for patient support program

Biobanks, research organizations and labs --- Research genomic profiles in-depth, often resulting in new biomarker identification, or re-classification Profile genomic characteristics of the acquired biospecimen to increase the value of your biospecimen assets

Health technology --- Leverage genetic information to provide precision health insights to your customers and users Generate real world evidence data including genetic information

Years in service: 3

Bioinformatics services offered by Inocras Inc.:

Service Description Price
Base Calling $335.00 USD (per hour)
Genome Annotation $335.00 USD (per hour)
Genome Mapping Restricted only to human genome. $335.00 USD (per hour)
Methylation Analysis $335.00 USD (per hour)
SNP / Indel Calling $335.00 USD (per hour)
SNP / Indel Mapping $335.00 USD (per hour)
SNP/SV/CNV Discovery $335.00 USD (per hour)
Transcriptome Annotation $335.00 USD (per hour)
Transcriptome Mapping $335.00 USD (per hour)
Variant Annotation $335.00 USD (per hour)

TAXON Bioinformatics Solutions S.A.

NGS provider 3 years in service Genome Annotation: $399.00 USD (per sample)
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We are TAXON, a data-driven bioinformatics team, specializing in high-confidence downstream analysis and client-ready delivery (not just raw outputs). What makes us unique is that we package sequencing data into actionable, decision-oriented results using reproducible pipelines, ML-ready datasets, and regulatory-grade reporting when needed.

What we specialize

Plasmid-focused analysis: assembly/curation support (incl. circularization checks), plasmid typing/replicons, mobility elements, gene-level annotation, and optional AMR/virulence marker screening when needed.

Microbial genomics & taxonomy: strain identification, ANI/phylogenomics, contamination/QC, comparative genomics, and traceability/fingerprinting.

Metagenomics: end-to-end processing and interpretation for complex communities, including soil metagenomes and waste / residue-derived samples (taxonomic + functional profiling, group comparisons, biomarkers, ML-ready tables).

Yeast & fungal genomics: assembly/QC, annotation, comparative analyses, and applied interpretation for R&D.

Biosynthetic potential (BGC mining): detection, annotation, prioritization, novelty assessment, and clear "what to test next" guidance.

Scientific & regulatory-ready writing: structured, audit-friendly documentation and reports when clients operate in regulated markets.

Custom ML & data science (on request): we develop and productionize ML models for biological/biotech use cases (bioinformatics, AgTech), including feature engineering from omics data, biomarker discovery, predictive modeling, and deployment-ready datasets/pipelines.

Organisms & systems we've worked with

Bacteria and plasmids, including deep expertise in the Bacillus subtilis group and Bacillus cereus group, with published work on taxonomy across related species.

Yeasts and fungi, including Komagataella phaffii, Pichia pastoris and Trichoderma.

Mixed microbial communities (microbiomes), especially from soil and natural environments.

Years in service: 3

Bioinformatics services offered by TAXON Bioinformatics Solutions S.A.:

Service Description Price
Base Calling Conversion of raw sequencing signal data into FASTQ files. Includes base calling, basic read quality assessment, and organized FASTQ delivery. Demultiplexing or additional QC can be included if specified in the project scope. 170.00
Comparative Genome Analysis Comprehensive comparative genome analysis across strains, species, or reference datasets. This service may include comparative gene content analysis, functional clustering, broader gene presence/absence screening, antiSMASH/BGC comparison, selected phylogenomic analyses, figures, summary tables, and a detailed technical report. Recommended for projects requiring biological interpretation beyond a… $665.00 USD (per sample)
Comparative Genome Analysis Comparative analysis of genomes or selected genomic features across strains, species, or reference datasets. This service may include ANI analysis, selected BLAST comparisons, gene presence/absence screening, basic phylogenetic placement, and summary tables. It is intended for focused comparisons with a limited number of genomes or predefined targets. Price per comparison 450.00
Custom scripting and special projects Custom bioinformatic scripting, workflow development, data parsing, figure generation, file conversion, automation, or ad hoc analysis not covered by standard services. Turnaround depends on scope and data complexity. $110.00 USD (per hour)
Differential Gene Expression Analysis Differential expression analysis between experimental conditions from a count matrix or normalized expression table. Includes statistical analysis, fold-change and significance tables, volcano/MA plots, PCA or clustering plots when appropriate, and a concise report. FASTQ processing and transcriptome mapping are quoted separately. Price per comparison 335.00
Genome Annotation Basic structural and functional annotation of simple eukaryotic genomes, such as yeasts or small fungal genomes. Includes gene prediction/annotation when suitable input data are available, functional assignment, GFF/GenBank/FASTA output files, annotation tables, and a concise technical report. Complex eukaryotic genomes, large genomes, or projects requiring transcriptome-guided/manual annotation … $399.00 USD (per sample)
Genome Annotation Structural and functional annotation of prokaryotic genomes. Includes gene prediction, CDS annotation, rRNA/tRNA detection, functional assignment, GFF/GenBank/FASTA output files, annotation tables, and a concise technical report. $199.00 USD (per sample)
Genome Mapping Alignment of genomic sequencing reads to a reference genome. Includes read mapping, alignment quality metrics, coverage summary, sorted/indexed alignment files, and a brief report. Variant calling or biological interpretation is not included unless requested separately. $220.00 USD (per sample)
Metagenomic Analysis Bioinformatic analysis of previously generated metagenomic sequencing data. Includes read quality control, filtering, taxonomic profiling, abundance tables, diversity summaries when applicable, and a concise report. Functional profiling may be included depending on data type and sequencing depth. $280.00 USD (per sample)
Microbiome Analysis Bioinformatic analysis of amplicon-based microbiome data, such as 16S, ITS, or similar marker-gene sequencing. Includes quality filtering, denoising/ASV or OTU inference, taxonomic assignment, abundance tables, alpha/beta diversity summaries, plots, and a brief report. $280.00 USD (per sample)
Other Services Bioinformatic consulting or custom analysis outside the listed service categories. Scope, deliverables, and turnaround are defined before project start. $110.00 USD (per hour)
Read Filtering and Cleaning Quality control and preprocessing of sequencing reads. Includes adapter trimming, low-quality read filtering, quality reports, cleaned FASTQ files, and a brief QC summary. Host/contaminant removal can be included if reference files are provided or specified. $110.00 USD (per sample)
SNP / Indel Calling Detection of SNPs and small insertions/deletions relative to a reference genome. Includes mapping review, variant calling, basic filtering, VCF file generation, variant summary tables, and a short technical report. $335.00 USD (per sample)
SNP / Indel Mapping Mapping of sequencing reads against a reference genome for downstream SNP and small indel analysis. Includes read alignment, sorting/indexing, basic alignment quality control, and delivery of BAM/CRAM files plus a short QC summary. $220.00 USD (per sample)
SNP/SV/CNV Discovery Discovery of SNPs, indels, structural variants, and/or copy number variation depending on the available sequencing data and reference genome quality. Includes variant tables, filtered output files, summary statistics, and a technical report. $450.00 USD (per sample)
Transcriptome Annotation Functional annotation of assembled prokaryotic transcripts or transcript sequences. Includes ORF prediction when applicable, similarity searches, domain/function assignment, annotation tables, and a concise technical report. $199.00 USD (per sample)
Transcriptome Annotation Functional annotation of assembled eukaryotic transcripts or transcript sequences. Includes ORF prediction when applicable, similarity searches, domain/function assignment, annotation tables, and a concise technical report. Complex transcriptomes, non-model organisms, or large datasets may require custom pricing. $399.00 USD (per sample)
Transcriptome de novo Assembly De novo assembly of transcriptomic reads without a reference genome. Includes read QC, transcript assembly, assembly quality statistics, transcript FASTA files, and a technical summary. Annotation is not included unless requested separately. $250.00 USD (per sample)
Transcriptome Mapping Mapping of RNA-seq reads to a reference genome or transcriptome. Includes read alignment, alignment QC, gene/transcript quantification when annotation is available, count/TPM tables, BAM files, and a short technical summary. $225.00 USD (per sample)
Whole Genome de novo Assembly De novo genome assembly from sequencing reads. Includes read QC, assembly generation, assembly quality statistics, contamination/quality checks when applicable, FASTA output, and a brief technical report. Complex eukaryotic genomes or hybrid assemblies may require custom pricing. $199.00 USD (per sample)